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Hoehe M, 1988. Affect of the menstrual cycle on neuroendocrine and behavioral responses to an opiate agonist in humans: preliminary results. PsychoneuroendocrinologyObserve Closely (2)efavirenz will lower the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Coadministration of f